Dull-looking skin
Example image slot showing a fresher and more radiant-looking complexion.
A skin-reviving PDRN facial combining a gentle chemical peel, PDRN and hyaluronic acid with Micropen application to support smoother-looking texture, lasting hydration and a fresh, radiant complexion.
Common skin issues
This treatment may be considered for selected skin concerns after your skin condition has been assessed.
Treatment overview
A PDRN facial is a skin-rejuvenating facial that combines PDRN with hydrating and resurfacing steps to improve the appearance of dry, dull and uneven-looking skin. At Bio Aesthetic Medispa, our PDRN Skin Revive Facial pairs a gentle chemical peel with PDRN 2%, hyaluronic acid and Micropen application, followed by a calming recovery mask.
PDRN stands for polydeoxyribonucleotide, a DNA-derived ingredient used in professional skincare for its skin-conditioning and rejuvenating properties. In our PDRN facial, it is combined with hyaluronic acid to support hydration and a smoother, more refreshed appearance.
The treatment begins with cleansing and a gentle chemical peel to prepare the skin. PDRN 2% and hyaluronic acid are then applied with a Micropen, allowing the treatment to be spread evenly and precisely across the face. The facial finishes with a recovery mask, calming skincare and sun protection.
The PDRN Skin Revive Facial is particularly suited to skin that appears dehydrated, dull, uneven in texture or affected by visible fine lines and early signs of ageing.
Key benefits
The PDRN Skin Revive Facial combines gentle exfoliation, PDRN 2%, hyaluronic acid and Micropen application to target several common signs of tired, dehydrated and ageing-looking skin in one treatment.
How it works
The 60-minute PDRN Skin Revive Facial combines gentle resurfacing, PDRN 2%, hyaluronic acid and Micropen application in a structured treatment designed to refresh, hydrate and improve the appearance of the skin.
The facial begins with a thorough double cleanse to remove surface impurities and prepare the skin for treatment.
A gentle chemical peel is applied to remove surface buildup and create a smoother, fresher-looking complexion before the PDRN stage.
The peel is carefully removed and the skin is prepared for the next stage of the facial.
PDRN 2% is combined with hyaluronic acid and applied across the face using a Micropen, allowing the formulation to be worked evenly and precisely over the treatment area.
A Cell Repair Recovery Mask is applied to soothe and hydrate the skin, while a relaxing shoulder massage completes the calming phase of the facial.
Calming skincare and sun protection are applied to complete the treatment and help keep the skin comfortable after the facial.
Compare treatments
Not every facial is designed for the same skin goal. PDRN Facial focuses on hydration, skin texture, radiance and early signs of ageing, while HydraFacial places greater emphasis on pore cleansing and extraction, and chemical peels focus primarily on exfoliation and resurfacing.
| Treatment | Main Focus | Key Treatment Elements | Best Suited For | Post-Treatment Response |
|---|---|---|---|---|
| PDRN Facial | Skin rejuvenation, hydration and texture | Gentle chemical peel, PDRN 2%, hyaluronic acid, Micropen application and recovery mask | Dehydrated or dull-looking skin, uneven texture, fine lines and early loss of firmness | Temporary redness or sensitivity may occur after treatment |
| HydraFacial | Deep pore cleansing and hydration | Hydradermabrasion, gentle peel, suction-based extraction and serum infusion | Oily skin, clogged pores, blackheads, enlarged-looking pores, dullness and dehydration | Minimal to no downtime for most clients |
| Chemical Peel Facial | Exfoliation and surface renewal | Selected exfoliating acid applied according to skin condition and tolerance | Dullness, rough texture, uneven-looking tone or congestion depending on the peel selected | Redness, sensitivity or light flaking may occur depending on peel strength |
Price
Pricing may vary depending on treatment focus, skin condition and whether a package or maintenance plan is chosen.
First trial
Final pricing may vary based on treatment focus and whether a package or maintenance plan is chosen. Prices are subjected to GST
Price breakdown
Compare the PDRN Facial first-trial and regular-session prices at Bio Aesthetic Medispa. Each 60-minute session includes the complete PDRN Skin Revive Facial protocol.
| Session | Price | Treatment Time | What It Includes |
|---|---|---|---|
| PDRN Facial First Trial | S$238 | 60 mins | Gentle chemical peel, PDRN 2%, hyaluronic acid, Micropen application, recovery mask, calming skincare and sun protection |
| Regular PDRN Facial | S$498 | 60 mins | Gentle chemical peel, PDRN 2%, hyaluronic acid, Micropen application, recovery mask, calming skincare and sun protection |
Personalised selection
Your PDRN Facial is tailored according to your current skin condition, hydration level, sensitivity, texture and treatment goals.
Before treatment, your therapist will assess your skin and determine how gently or intensively each stage should be carried out. This is particularly important for the chemical peel and Micropen stages.
Your treatment plan may also be adjusted between sessions depending on how your skin responds.
Skin concern guide
Different skin concerns may benefit from a different treatment emphasis. Your therapist will assess your skin condition, sensitivity and treatment goals before adjusting the PDRN Facial approach.
| Skin Concern | How PDRN Facial May Help | Treatment Focus |
|---|---|---|
| Dry & Dehydrated Skin | Supports a more hydrated, comfortable and refreshed-looking complexion. | PDRN 2% and hyaluronic acid with calming and hydrating care. |
| Dull-Looking Skin | Helps refresh tired-looking skin and improve the appearance of radiance. | Gentle chemical peel followed by PDRN and hydrating skincare. |
| Uneven Skin Texture | Helps improve the appearance of roughness and uneven surface texture. | Gentle exfoliation combined with controlled Micropen application. |
| Fine Lines & Early Ageing | Supports smoother, more refreshed-looking skin and can soften the appearance of fine lines. | PDRN 2%, hyaluronic acid and targeted Micropen application. |
| Visible Marks & Uneven Tone | May help improve the overall appearance of visible marks and uneven-looking skin tone. | Careful exfoliation and targeted treatment based on skin tolerance. |
| Loss of Firmness | Supports skin that appears less firm, resilient or refreshed with age. | PDRN-focused skin rejuvenation with hydration and recovery care. |
Reviews
Read what clients say about their Bio Aesthetic Medispa experience.
Before and after
Real People, Real Results
Example image slot showing a fresher and more radiant-looking complexion.
Example image slot showing brighter-looking and more even-looking skin.
Example image slot for smoother and more hydrated-looking skin.
Example image slot showing a more refined-looking surface.
Individual results vary. Before-and-after images are shown for general illustration or with client consent where applicable. A consultation is recommended to assess skin condition and suitability.
FAQ
You may feel light prickling or tingling during the Micropen stage. The treatment is performed without numbing cream, and the Micropen depth is adjusted according to the skin area and tolerance.
The treatment protocol is designed to allow Micropen application without numbing cream. When performed without numbing, the treatment depth is controlled between 0.2 and 1 mm and should not exceed 1 mm.
Avoid makeup for 24–48 hours after treatment to give the skin time to settle.
Wait at least 1 week before having another facial treatment.
Mild peeling or flaking can occur. Do not pick or pull at peeling skin, as this can interfere with the skin's recovery. Keep cleansing gentle and moisturise well.
Not when acne or rosacea is actively inflamed. Both active acne and inflammatory rosacea are listed as contraindications in the treatment protocol.
No. Pregnancy and breastfeeding are listed as contraindications for this treatment.
The protocol excludes clients who have taken isotretinoin within the previous 6 months.
The peel is removed and neutralised if excessive irritation develops. If irritation is significant, the Micropen stage is not performed; the treatment moves instead to the calming and recovery steps.
The PDRN used in this treatment is described by the product protocol as being derived from recycled marine-source DNA fragments. The protocol does not specifically identify the source as salmon, so we do not market it as “salmon DNA.”
Contact Us
Let us assess your skin condition, visible concerns and treatment goals before recommending a suitable facial treatment plan.

Skin-first planning
Our team considers your skin condition, sensitivity, lifestyle and treatment goals before recommending a facial plan.
Locations
Choose the outlet that is most convenient for your visit.
PDRN Facial is available at Bio Aesthetic Medispa Orchard and Tampines. Choose your preferred outlet for a skin assessment and personalised treatment plan based on your skin condition, sensitivity and goals.
390 Orchard Road, #03-01 Palais Renaissance, Singapore 238871
300 Tampines Avenue 5, #04-05 Income at Tampines Junction, Singapore 529653
Education
Helpful information before you book your session.
PDRN stands for polydeoxyribonucleotide, a DNA-derived ingredient from marine sources. In our PDRN Facial, PDRN 2% is combined with hyaluronic acid as part of a multi-step treatment for hydration, texture and overall skin rejuvenation.
Keep your skincare gentle after treatment. Avoid exfoliating acids, scrubs and retinoids for 3–5 days, avoid heat such as saunas and steam for at least 48 hours, moisturise well and protect the skin carefully from direct sun exposure.
A PDRN Facial and an injectable PDRN skin booster are different treatments. Bio Aesthetic’s PDRN Skin Revive Facial is a non-injectable facial that combines PDRN 2% and hyaluronic acid with Micropen application, a gentle chemical peel and calming skincare.
Book your facial
Book a skin assessment at Bio Aesthetic Medispa to find out whether the PDRN Skin Revive Facial suits your hydration, texture, radiance and early ageing concerns. Your therapist will recommend a treatment approach based on your skin condition and goals.